Models Publication List

ALS PDC Model

 

Tabata, R. C., Wilson, J. M. B., Ly, P., Zwiegers, P., Kwok, D., Van Kampen, J. M., Cashman, N., & Shaw, C. A. (2008). Chronic Exposure to Dietary Sterol Glucosides is Neurotoxic to Motor Neurons and Induces an ALS–PDC Phenotype.Neuromolecular medicine, 10(1), 24-39.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814814/

Wilson JM, Khabazian I, Wong MC, Seyedalikhani A, Bains JS, Pasqualotto BA, Williams DE, Andersen RJ, Simpson RJ, Smith R, Craig UK, Kurland LT, Shaw CA. (2002). Behavioral and neurological correlates of ALS-parkinsonism dementia complex in adult mice fed washed cycad flour. Neuromolecular Medicine, 1(3), 207-221.

http://dx.doi.org/10.1385/NMM:1:3:207

 

Parkinson’s Disease Model

 

Van Kampen JM, Baranowski DC, Robertson HA, Shaw CA, Kay DG. (2015). The Progressive BSSG Rat Model of Parkinson’s: Recapitulating Multiple Key Features of the Human Disease. PLoS One 10(10): e0139694.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595214/

Van Kampen, J. M., Baranowski, D. B., Shaw, C. A., & Kay, D. G. (2014). Panax ginseng is neuroprotective in a novel progressive model of Parkinson’s disease. Experimental Gerontology, 50, 95-105.

http://www.sciencedirect.com/science/article/pii/S0531556513003410

 

Epilepsy Model

 

Doucette, T. A., Bernard, P. B., Husum, H., Perry, M. A., Ryan, C. L., & Tasker, R. A. R. (2004). Low doses of domoic acid during postnatal development produce permanent changes in rat behaviour and hippocampal morphology. Neurotoxicity Research, 6(7), 555–563.

http://link.springer.com/content/pdf/10.1007/BF03033451.pdf

Gill DA, Bastlund JF, Anderson NJ, Tasker RA. (2009). Reductions in paradoxical sleep time in adult rats treated neonatally with low dose domoic acid. Behavioural Brain Research. 205(2):564-7

http://www.sciencedirect.com/science/article/pii/S0166432809004380