CNS|CRO offers a wide range of behavioural tests for in vivo assessments, and have the expertise to assist in designing a test battery specific to your needs. If required, many tests may be adapted and/or combined with additional techniques to provide client-tailored in vivo assessments. Histological analyses (e.g. morphology, immunohistochemistry, etc) are also available. All work is properly blinded and behaviours are digitally recorded for arms-length evaluation and provided as a record with the final report.
Available tests include the elevated plus maze, light-dark box, open field, and forced swim test.
Conditioned Place Preference
Learning and Memory
Various test paradigms exist to explore learning and memory and can be run in either simple or complex configurations to detect different degrees of functional alteration. Among others, CNS|CRO offers the Morris Water Maze, Novel Water Maze, Radial Arm Maze and Barnes Circular Maze to test spatial learning and memory. These tests all require integrity of the hippocampal formation and associated structures. All paradigms can be run in cued or uncued configurations. Depending upon the parameters used, T- and Y-mazes can assess either operant conditioning (e.g. cued tasks) or spatial learning (e.g. reliance on egocentric cues).
Gross and Fine Motor Function
The Learning - Performance Distinction
Learning is assessed by performance. However performance is determined by factors other than learning alone, including opportunity, motivation and sensory-motor capabilities. CNS|CRO offers expertise in identifying those aspects of performance which are due to learning and/or memory processes and designing established and novel paradigms under the direction of senior scientists who collectively have over 65 years of experience in the behavioural testing field.